NIST Cements America’s Edge in AI and Critical Infrastructure

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The U.S. National Institute of Standards and Technology (NIST) is making a decisive move to strengthen America’s position in artificial intelligence. The agency has announced a $20 million initiative to launch two dedicated AI centers focused on U.S. manufacturing and critical infrastructure. In partnership with nonprofit MITRE Corporation, the program aims to speed up AI deployment in sectors central to economic strength and national security.

According to Deputy Secretary of Commerce Paul Dabbar, the investment is meant to accelerate AI adoption across American manufacturing. As a result, manufacturers could boost productivity, improve global competitiveness, and attract new capital. More broadly, the effort reflects a growing push to link AI innovation directly to industrial outcomes.

AI at the Heart of Industrial and Security Strategy

The initiative will establish two entities: the AI Economic Security Center for U.S. Manufacturing Productivity and the AI Economic Security Center focused on protecting critical infrastructure from cyber threats. Together, these centers will deploy AI agents to improve factory efficiency, reduce supply chain risks, and counter emerging cyber vulnerabilities. Importantly, the focus is not research alone, but real-world deployment.

At the same time, the strategy aligns with the White House’s July 2025 America’s AI Action Plan. Specifically, it supports Pillar I, which prioritizes accelerating AI innovation, and Pillar II, which emphasizes building domestic AI infrastructure. Through this framework, NIST plans to expand public-private collaboration while advancing research in areas such as quantum information science and biotechnology.

Building on Existing AI Leadership and Partnerships

These new centers build on NIST’s existing AI portfolio, including the Center for AI Standards and Innovation (CAISI). Currently, CAISI works with leading AI developers to evaluate frontier systems and establish voluntary best practices for national security use cases. By adding MITRE’s experience in operating federally funded R&D centers, NIST expects faster translation from testing to deployment.

Meanwhile, NIST is preparing to announce funding for the AI for Resilient Manufacturing Institute under the Manufacturing USA program. The institute is expected to receive $70 million over five years, supported by both federal and nonfederal contributions. Its mandate will be to integrate AI into supply chains and manufacturing networks at scale.

Taken together, these initiatives signal a coordinated push to defend U.S. leadership in AI. As global competitors scale rapidly, NIST is tying AI progress directly to manufacturing strength and infrastructure resilience. In doing so, the agency is positioning AI not as an abstract capability, but as a concrete driver of economic and strategic advantage.

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